embryo implantation

Primary Cilia Length in Uterus Key to Embryo Implantation, Study Finds

A research team led by Tsai Shao-cheng has discovered that the length of primary cilia in the uterine lining is crucial for successful embryo implantation. The study, supported by the National Science and Technology Council, found that these cilia shorten with age and in women with endometriosis. Using a drug to inhibit TGF-β1 signaling restored cilia length in mice, increasing pregnancy rates by 40%.