Poolbeg Pharma will trial its oral drug POLB 001 at six NHS hospitals to prevent cytokine release syndrome (CRS), a dangerous side-effect of cancer immunotherapy. The drug could improve patient safety and save healthcare systems millions by allowing treatment outside specialist centers.
A nutritionist advises that excessive protein intake, especially when combined with insufficient vegetables and carbohydrates, can hinder metabolism, lead to fat accumulation, and cause fatigue, constipation, and thirst. She recommends balanced meals with plant-based proteins and complex carbohydrates for sustainable weight loss and muscle gain.
The article explores drug repurposing, highlighting GLP-1 agonists like Ozempic and Wegovy, initially for diabetes, now used for weight loss, cardiovascular health, and more. It also discusses COVID-19 treatments like dexamethasone and baricitinib, and historical examples like raloxifene, thalidomide, BCG vaccine, and Viagra, emphasizing both the benefits and potential risks of using drugs for unapproved conditions.
This report covers three health topics: distinguishing chest pain from heart issues vs. muscle strain, the benefits of adding honey to tea, and a study on gut bacteria aiding long-term weight maintenance.
US regulators are warning consumers about potential kidney problems linked to GSK's Alli weight loss pill. The FDA identified 12 cases of kidney complications and advises those with kidney history to consult a doctor.
The UK's MHRA has approved the first GLP-1 receptor agonist tablet, semaglutide (Wegovy), for weight loss and management. This daily pill offers a more convenient alternative to weekly injections for adults with obesity or those overweight with weight-related conditions.
Recent studies suggest GLP-1 obesity treatments may reduce cancer risk, showing correlation with decreased incidence in 6 out of 7 cancers, potentially through anti-inflammatory effects beyond weight loss.
Dr. Emily Leeming clarifies that sugar itself isn't inherently harmful but rather the context in which it's consumed, highlighting the importance of overall diet quality and distinguishing between added 'free sugars' and natural sugars in whole foods.
A Reddit user lost nearly 70 pounds by avoiding common weight-loss pitfalls like extreme restriction and guilt. They emphasize realistic eating, addressing emotional hunger, consistent exercise, and recovering quickly from setbacks.
Chinese health experts caution against extreme weight loss trends like "carb face" and "lying flat weight loss" injections. They stress that healthy weight management focuses on balanced nutrition, muscle preservation, and lifestyle changes, not just rapid weight reduction. The national "Weight Management Year" initiative encourages a holistic approach.
Novo Nordisk has launched its weight loss pill Wegovy in the United Arab Emirates, marking its first expansion outside the US. The drug, approved for weight management and cardiovascular risk reduction, faces increasing competition in the growing obesity drug market.
Novo Nordisk has launched its weight loss pill Wegovy in the United Arab Emirates, marking its first expansion outside the U.S. market. The drug's approval by the Emirates Drug Establishment follows recent competition from Eli Lilly in the growing obesity drug sector.
Osaka Prefectural Police have referred three individuals, aged 22-35, to prosecutors for allegedly selling Eli Lilly's diabetes drug 'Mounjaro' without authorization, often marketed as a weight-loss aid on social media. This marks the first such case for the Osaka police and is rare nationwide.
Actor John Goodman, 73, has undergone a significant physical transformation, losing over 90 kilos. He attributes the change to health reasons, a gradual process starting in 2007 involving sobriety, a personal trainer, diet changes, and consistent exercise.
US President Donald Trump, 79, is declared in 'excellent health' by his physician, Dr. Sean Barbabella, after a routine medical examination, despite recommendations for weight loss and increased physical activity.
US President Donald Trump, 79, is deemed in 'excellent health' by his physician, Dr. Sean Barbabella, after a comprehensive medical exam, despite recommendations for weight loss and increased physical activity.
CVS Health will restore coverage of Eli Lilly's weight loss injection Zepbound on Oct. 1 and add coverage of its new obesity pill Foundayo on June 1, making both GLP-1 medications co-preferred options on its standard commercial formulary, affecting 25-30 million Americans and boosting Lilly's market position against Novo Nordisk.
Retatrutide, a new obesity drug from Eli Lilly, has shown a 30% weight loss in trials, surpassing previous drugs like Ozempic. It mimics GLP-1 and other hormones, offering benefits beyond weight loss, including anti-inflammatory effects.
Retatrutide, a new obesity drug, has shown a 30% weight loss in trials, surpassing previous drugs. Experts highlight its broader benefits beyond weight loss, including reduced inflammation and improved cardiovascular and kidney function, attributing these to its multi-organ receptor action.
Florida's 'Alligator Alcatraz' immigration jail, criticized for inhumane conditions and high costs, is closing. Detainees like Justo Betancourt suffered severe health issues, with doctors suspecting strokes exacerbated by poor medical care and an ankle monitor preventing MRI scans. Governor Ron DeSantis, who championed the facility, is now distancing himself from it.
Nutritionist Liao Xin-yi explains that prolonged calorie restriction can lead to weight loss plateaus due to decreased metabolism, muscle loss, increased stress hormones, and reduced NEAT. She advises against extreme calorie deficits and emphasizes adequate protein, maintaining muscle mass, activity, sleep, and stress management.
A new drug called retatrutide has shown significant weight loss results in a study, with participants losing up to 28.3% of their body weight. The drug targets three hormonal pathways simultaneously, leading to greater weight loss than current medications.
Eli Lilly's new obesity drug, retatrutide, showed significant weight loss in a late-stage trial, with the highest dose leading to an average loss of 28.3% over 80 weeks. The drug targets three gut hormones and appears more effective than existing treatments, bringing Lilly closer to regulatory approval.
A Peking Union Medical College Hospital physician advises caution with rapid weight loss methods, including "slimming injections" and diabetes medications. These are prescription drugs with specific indications and potential side effects, requiring specialist evaluation and not for self-purchase or arbitrary use. The expert specifically warns against their use in individuals under 18 due to potential impacts on growth and development.
