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BackScientists have linked hypertension to the activity of the brain's respiratory center
Scientists have linked hypertension to the activity of the brain's respiratory center
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Лента.ру1 hour agoHealth1 min readRussiaView original

Scientists have linked hypertension to the activity of the brain's respiratory center

Quick Look

  • Researchers have found that the lateral parafacial area of ​​the brain (pFL), which is responsible for breathing, sends signals in hypertension that constrict blood vessels and increase blood pressure.
  • Suppressing this activity in rats normalized blood pressure.
  • The discovery may explain the link between sleep apnea and hypertension.

AI-generated summary

Why It Matters

Hypertension is a common disease associated with an increased risk of cardiovascular complications. The lateral parafacial region (pFL) of the brain typically regulates breathing during exercise, coughing, or laughter.

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One reason for high blood pressure may be activity in the part of the brain that controls breathing. Scientists have found that in case of hypertension, it can send signals that cause vasoconstriction and an increase in pressure. The study results were published in the journal Circulation Research (CR).

The researchers studied an area of ​​the brain called the lateral parafacial area (pFL). It is usually involved in controlling breathing, such as during exercise, coughing or laughing. However, experiments on rats have shown that in hypertension, its neurons can also affect blood vessels.

When scientists activated these cells, the work of the sympathetic nervous system increased, the blood vessels narrowed, and the pressure increased. When activity in the same region was suppressed in hypertensive rats, blood pressure returned to normal.

According to the researchers, the discovery may also explain why sleep apnea is associated with an increased risk of hypertension. When breathing stops, oxygen levels decrease and carbon dioxide levels increase, which can activate the discovered mechanism.

Now scientists want to find a way to influence it without intervening directly in the brain.

What to Watch

AI outlook — possibilities, not facts

  • Scientists will find a way to target the lateral parafacial region of the brain without direct neurosurgical intervention.

    Possible · Within months

Open Questions

  • How exactly can you target the pFL without directly interfering with the brain?
  • Will the results of the study be confirmed in humans?
  • What drugs or methods can block this mechanism?

Related Topics

This article was originally published by Лента.ру.

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