
AI-generated summary
Scientists analyzed 69 studies involving nearly 4.5 million people to identify links between lifestyle and cognitive health.
Sleeping seven to eight hours a night is associated with the lowest risk of developing dementia. Both too little and too much sleep were associated with an increased risk of disease. This conclusion was reached by scientists at York University in Canada. The results of their study were published in the journal PLOS One.
The authors analyzed data from 69 previous studies that included a total of nearly 4.5 million people. In addition to sleep duration, the researchers assessed the effects of physical activity and time spent sitting.
Compared to the optimal seven to eight hours, sleeping less than seven hours a night was associated with an 18 percent increased risk of dementia. People who slept more than eight hours had a 28 percent higher risk.
Additional risk factors were lack of movement and prolonged sitting. Less than 150 minutes of physical activity per week and more than eight hours of sedentary activity per day were also associated with a greater likelihood of developing dementia.
The authors note that sleep, movement, and physical activity can support blood flow to the brain, normal nerve cell function, and reduce inflammation. However, the study found an association, but did not prove that too little or too much sleep directly causes dementia.

A Vanderbilt University Medical Center study found that empagliflozin reduced inflammatory monocyte and platelet aggregates in obese women with prediabetes after just two weeks, an effect that increased over three months and was not observed in the low-calorie diet group, suggesting a direct anti-inflammatory effect of the drug beyond weight loss.

Tectochrysin, a natural compound from propolis, reduced the viability and proliferation of colorectal cancer cells in laboratory experiments and reduced tumor activity and metastases in the liver and lungs in mice by suppressing signaling pathways through the ERBB4 protein, but its effect in humans has not yet been studied.

Director of the National Medical Research Center for Endocrinology Natalya Mokrysheva said that in the coming decades the creation of a universal cure for diabetes is impossible due to the lack of a single monogenic cause of the disease.

A study published in the journal Science found that hypertension accelerates osteoarthritis through the hormone vasopressin. Scientists have found that blocking AVPR1A receptors in joints can prevent cartilage breakdown caused by high blood pressure.

Deputy Minister of Health of the Russian Federation Sergei Glagolev said that the increase in prices for vital and essential medicines in Russia remains below the inflation rate.

Russian sanitary watchdog Rospotrebnadzor has offered to assist the United States in managing recent outbreaks of infectious diseases, including measles, typhus, and plague, citing Russia's experience in epidemiological control.