Dr. Zeng Jianhua, director of the critical care department of Shuanghe Hospital of the Ministry of Health and Welfare, shared the treatment methods for sepsis. (Taken from the post)
A female nurse in her 40s with a family history of diabetes recently developed a high fever due to a urinary tract infection. Although she went to the emergency room as soon as possible, the disease progressed rapidly and has evolved into sepsis. The medical team immediately arranged broad-acting antibiotics, massive infusions, and two lines of high-dose vasopressors. Her blood pressure and condition were still difficult to control, and edema had begun to appear throughout her body. After examination, it was found that the nurse was infected with the highly virulent Klebsiella pneumoniae. Because she was young and had a strong immune response, the inflammatory response in her body remained high. At the suggestion of the medical team, blood purification treatment was introduced to quickly remove excessive cytokines and bacterial toxins in the blood through a special adsorption membrane. She finally successfully removed the vasopressor, gradually regained consciousness, and was out of danger.
Infection causes systemic inflammation, and the mortality rate of severe sepsis is about 50%
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Common local infections such as pneumonia, urinary tract infection or cellulitis can often be controlled with appropriate antibiotic treatment. However, if pathogens or their toxins invade the blood circulation and trigger a systemic immune out-of-control response, they can evolve into life-threatening sepsis. Dr. Zeng Jianhua, director of the critical care department of Shuanghe Hospital of the Ministry of Health and Welfare, explained that sepsis is an infection combined with a systemic inflammatory reaction. Bacteria spread from the original site to the bloodstream, prompting the immune system to overreact, which then evolves into systemic destruction. Once sepsis is complicated, blood vessels throughout the body will expand and organ perfusion will be insufficient, and the mortality rate in severe cases will suddenly rise to more than 40% to 50%. Clinical treatment is an uphill battle against time.
Don’t ignore the rapid heartbeat and sudden drop in blood pressure. These are four critical warning signs and you should seek medical attention immediately.
Many patients often mistake the early signs of sepsis for a common cold or a common fever and delay seeking medical treatment, causing the condition to rapidly worsen in a short period of time. Dr. Tsang Jianhua emphasized that it may only take a few hours to a day or two for local infection to develop into systemic sepsis. If in addition to fever, there are warning signs such as rapid heartbeat, rapid breathing, low blood pressure, and changes in consciousness, it means that the inflammatory reaction has spread throughout the body and is by no means a simple local infection. You must seek medical treatment immediately to avoid missing the golden period of rescue.
It may only take a few hours to a day or two for local infection to develop into systemic sepsis. If in addition to fever, there are warning signs such as rapid heartbeat, shortness of breath, low blood pressure, and changes in consciousness, it means that the inflammatory response has spread throughout the body. (Taken from the post)
Anyone can develop sepsis due to infection, but clinically, the elderly, diabetics, patients with chronic diseases, or those with poor immune function, such as those who have taken steroids for a long time, are at a significantly higher risk of developing the disease and severe illness. Dr. Tsang Jianhua called on the most fundamental way to prevent sepsis is to block local infection at the source. For example, patients with diabetes should take good care of foot wounds to prevent cellulitis. Elderly people who are prone to choking should strengthen swallowing training or evaluate tube irrigation to reduce the risk of aspiration pneumonia. Do not hold urine and maintain adequate fluids to prevent urinary tract infections. Only by implementing daily infection control can the incidence be reduced.
Traditional antibiotics and vasopressors encounter bottlenecks, and blood purification technology removes toxins and cytokines in a timely manner
In the routine treatment of sepsis, antibiotics are used together with infusion and vasopressors to maintain blood pressure and blood perfusion. If the patient's blood pressure still cannot stabilize and the inflammatory response continues to worsen, the body is often filled with excessive inflammatory mediators and toxins. Dr. Tsang Jianhua further explained that the principle of blood purification is like "reducing a fever" in an immune storm. A catheter line is established through the deep jugular vein or femoral vein to drain the blood into an artificial kidney machine with a special adsorption membrane. It filters out excess cytokines and bacterial toxins and adjusts the immune response back to a reasonable range. It not only avoids excessive inflammation and damages the autologous organs, but also greatly reduces the burden of pulmonary edema and tissue edema caused by excessive infusion.
The principle of blood purification is like "reducing fever" in an immune storm. A catheter is established through the deep jugular vein or femoral vein to drain the blood into an artificial kidney machine with a special adsorption membrane to filter out excess cytokines and bacterial toxins and adjust the immune response back to a reasonable range. (Taken from the post)
Every second counts in the treatment of sepsis, seize the golden period to seize the opportunity for organ repair
Dr. Zeng Jianhua pointed out that in the face of the threat of sepsis, the most regrettable thing in clinical practice is that patients often tolerate discomfort, delay treatment, and wait until multiple organ failure occurs before seeking treatment, which greatly increases the difficulty of treatment. The public is reminded that if symptoms of infection are found, or even abnormal signs such as shortness of breath, rapid heartbeat, low blood pressure, or changes in consciousness, they should immediately go to the hospital for diagnosis and treatment, and make good use of treatment methods such as blood purification at critical moments to block the worsening of inflammation. Only in this way can the risk of death be effectively reduced and the organs given an opportunity to repair and recover!
The public is reminded that if symptoms of infection are found, or even abnormal signs such as shortness of breath, rapid heartbeat, low blood pressure, or changes in consciousness, they should go to the hospital for diagnosis and treatment immediately. (Taken from the post)
Organize notes in key points
● Sepsis is essentially an infection combined with a systemic inflammatory reaction. Bacteria spread from the original site to the bloodstream, prompting the immune system to overreact, which then evolves into systemic destruction. Clinical treatment is an uphill battle against time.
● It may only take a few hours to a day or two for local infection to evolve into systemic sepsis. If the patient is found to have a fever, rapid heartbeat, shortness of breath, low blood pressure, changes in consciousness and other warning signs, it means that the inflammatory reaction has spread to the whole body and requires immediate medical treatment.
● In the routine treatment of sepsis, antibiotics are used along with infusion and vasopressors to maintain blood pressure and blood perfusion. If the patient's blood pressure still cannot stabilize and the inflammatory response continues to worsen, the body is often filled with excessive inflammatory mediators and toxins.
● The principle of blood purification is like "reducing a fever" in an immune storm. A catheter is established through the deep jugular vein or femoral vein to drain the blood into an artificial kidney machine with a special adsorption membrane. It filters out excess cytokines and bacterial toxins and adjusts the immune response back to a reasonable range. It not only avoids excessive inflammation and damages the autologous organs, but also greatly reduces the burden of pulmonary edema and tissue edema caused by excessive infusion.
This article is reprinted with permission from [Care Online] A small infection turns into a big crisis! The mortality rate of severe sepsis may reach 50%. Every second counts for treatment! Early introduction of blood purification technology to protect organs, expert doctors explain with pictures and texts
