
专家呼吁早识别、早筛查、科学管理神经内分泌肿瘤
11月10日世界神经内分泌肿瘤日,重庆大学附属肿瘤医院举行科普宣传与公益义诊活动。专家指出该病异质性强、极易误诊,呼吁公众提高科学认识,实现早筛早诊和规范化诊疗。
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11月10日是世界神经内分泌肿瘤日,旨在提高公众对该类少见肿瘤的科学认识。
中新网重庆11月10日电 (梁钦卿)11月10日是“世界神经内分泌肿瘤日”。为提高公众对神经内分泌肿瘤的科学认识,推动早筛早诊和规范化诊疗,重庆大学附属肿瘤医院10日以“早识别、早筛查、科学管理神经内分泌肿瘤”为主题,开展科普宣传和公益义诊活动。
人体全身分布着很多“神经内分泌细胞”,它们就像身体的小管家,负责分泌一些物质,帮助调节胃肠蠕动、心率和血糖。如果这些细胞失控、慢慢长成肿块,就是“神经内分泌肿瘤”。
图为重庆大学附属肿瘤医院以“早识别、早筛查、科学管理神经内分泌肿瘤”为主题,为过往市民开展科普宣传和公益义诊活动。重庆大学附属肿瘤医院供图
重庆大学附属肿瘤医院消化内科副主任廖忠莉介绍,虽然神经内分泌肿瘤的名字里带“神经”二字,却并非神经系统肿瘤;它可发生于全身多个器官,多见于胃肠道、胰腺和肺部。
廖忠莉称,1年前,62岁的李女士因“腹痛、便血”前往医院治疗,辗转多家医院仍未能明确病因。半年前,李女士来到重庆大学附属肿瘤医院,经系统检查,最终确诊为“直肠神经内分泌肿瘤”,且已出现肝、胰腺等多处转移。
“这是神经内分泌肿瘤临床诊断困境的一个缩影——异质性强、症状隐匿、极易被误诊,患者往往需要辗转多科室、多地求诊才能明确诊断。”廖忠莉介绍。
面对严峻病情,消化内科团队为她制定了阶梯式、多维度的综合治疗方案。在多学科专家共同护航下,李女士的病情得到有效控制,生活质量明显提高。
廖忠莉说,由于部分神经内分泌肿瘤细胞能分泌激素,患者可能出现反复腹泻、胃痛、皮肤潮红、低血糖、反复胃溃疡等,这些表现常被误认为普通肠胃病、皮肤病或其他慢性病。
出现哪些情况应尽早到专科医院就诊?“长期反复不明原因腹泻、阵发性皮肤潮红、难治性溃疡;胃镜/肠镜偶然发现黏膜下隆起、息肉样病灶;有神经内分泌肿瘤家族史、多发性内分泌腺瘤病(MEN1)家族史;体检发现嗜铬粒蛋白A升高、胰腺/肠道不明包块。”廖忠莉强调,若症状反复出现、原因不明,应尽早到专科医院就诊,避免错失最佳诊疗时机。
查出神经内分泌肿瘤就等于宣判“绝症”吗?并非如此。神经内分泌肿瘤并非单一病种,而是一大类生物学行为差异很大的肿瘤。只要早发现、早诊断,很多患者经过规范治疗能够获得长期生存。
目前,重庆大学附属肿瘤医院集结消化内科、肿瘤内科、病理科、影像科、核医学科、肝胆外科、胃肠外科、介入科、内分泌科等多学科专家,建立多学科质量保障体系。团队通过多种检查手段精准定位肿瘤、明确分化程度,再综合评估肿瘤部位、功能状态等,为患者制定个体化治疗方案。

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