Cargo plane overruns runway at Miami International Airport, multiple patients reported

There are "multiple patients" after a cargo plane crashed at Miami International Airport on Sunday, according to local fire officials. It's not clear whether anyone was killed in the incident.

Video posted on social media shows an Amazon Prime Air plane, a Boeing 767, off the runway with its tail over the fence and thick black smoke rising from the aircraft.

Miami-Dade Fire Rescue said there are "multiple patients" and that firefighters were working to extinguish the fire, calling it an active scene with over 60 MDFR units responding.

The cargo plane overran a runway after landing at the airport around 2 p.m. ET, the Federal Aviation Administration said in a statement to NPR. It said Flight 7598 originally took off from Luis Muñoz Marín International Airport in San Juan, Puerto Rico. The FAA said it will investigate the crash.

The Miami-Dade Aviation Department said in a statement that the plane overran the diagonal runway and is disabled at the northwest end of the airport. "All runways and taxiways at MIA are currently closed as of 3:00 p.m.," the department said. The FAA on Sunday issued a ground stop on planes until 3 p.m. that was later extended until 5:30 p.m. Transportation Sec. Sean Duffy said the ground stop was ordered so that first responders could assess the scene and warned travelers of "significant delays and potential cancellations."

At the time of the crash, the plane was being operated by the contract cargo carrier 21 Air, according to Amazon spokesperson Kelly Nantel.

"This is a fast-moving situation and we're still gathering details. We're working closely with local authorities and officials to understand exactly what happened," Nantel said in a post on social media. "Right now, our absolute priority is the safety, well-being, and care of everyone involved. We're doing everything we can to support those affected."

This is a breaking story and will be updated.