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Back研究:植物性原型飲食可降LDL-C 17.9%,但無法取代藥物治療
研究:植物性原型飲食可降LDL-C 17.9%,但無法取代藥物治療
Health
自由时报2 hours agoHealth2 min readChina

研究:植物性原型飲食可降LDL-C 17.9%,但無法取代藥物治療

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恆新復健科診所醫師王思恒引用《Nature Communications》研究指出,家族性高膽固醇患者攝取熱量逾8成來自植物性原型食物四週後,LDL-C降低17.9%,ApoB下降超過14%,但強調飲食無法取代必要藥物治療。

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Why It Matters

家族性高膽固醇是遺傳性疾病,導致低密度脂蛋白膽固醇異常升高,增加心血管疾病風險。傳統治療依賴藥物,但飲食調整常被視為輔助手段。

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2026/09/09 08:26

恆新復健科診所醫師王思恒表示,研究指出,飲食吃對有助壞膽固醇下降,但也提醒,飲食仍無法取代原本需要的藥物治療;示意圖。(圖取自freepik)

〔健康頻道/綜合報導〕具有家族性高膽固醇基因,控制飲食也沒用?對此,恆新復健科診所醫師王思恒表示,1項最新研究將受試者分為2組,一組以原型植物食物為主、一組以標準美式飲食為主,時間持續4週。結果發現,相較於美式飲食組,攝取熱量逾8成來自原型植物食物的受試者,低密度脂蛋白膽固醇(LDL-C)降低17.9%。不過,他也提醒,飲食仍不能取代患者原本需要的藥物治療。

王思恒於臉書粉專發文表示,2026年1篇發表在《Nature Communications》的研究,納入50名基因確診的家族性高膽固醇成人,讓他們分別吃兩種飲食各4週:一種是標準美式飲食,另一種則是以原型植物食物為主的飲食,而且食物幾乎都由研究團隊提供。

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植物性原型食物助降膽固醇

王思恒說明,研究中的植物性飲食,並不是完全不碰動物性食物,仍可攝取魚、蛋、乳製品,甚至少量雞肉、紅肉,但大幅提高蔬菜、水果、全穀、豆類等食物比例。此外,蛋白質來源大量換成豆腐、豆漿、黃豆製品、豆類、堅果種子,而且幾乎沒有香腸、培根、火腿等加工食品;至於精製澱粉、超加工食物、含糖飲料也明顯變少。整體來說,約82%熱量來自植物性食物,但不是純素,而是把飲食內容大幅朝植物性原型食物調整。

心血管風險也降低11.9%

研究結果顯示,相較標準美式飲食,採取植物性原型食物的受試者飲食4週後,LDL-C降低17.9%,ApoB下降超過14%、三酸甘油脂也降低。此外,血壓約下降2 mmHg,推估10年心血管疾病風險則降低11.9%。

避免極端 飲食不能取代藥物

不過,王思恒強調,研究結果雖顯示,受試者調整飲食後LDL下降將近18%,並不代表家族性高膽固醇患者單靠飲食就能達到治療目標。他表示,對於家族性高膽固醇患者來說,這篇研究同時打臉2種極端觀念:認為基因決定一切,吃什麼都沒差;或是只要吃得乾淨,就不用靠藥物;其實均非正確觀念。

王思恒強調,對家族性高膽固醇者來說,控制膽固醇的答案,通常不應是二選一,而是「藥物不能取代飲食,飲食也不能取代該吃的藥」。

Open Questions

  • 該研究的長期追蹤結果如何?
  • 植物性原型飲食對其他血脂指標的具體影響是什麼?
  • 不同年齡或性別的患者對此飲食的反應是否有差異?

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