Major police incident underway in Perth's south

Police are responding to reports of a serious incident at a rural property south of Perth.

One person has been arrested following a major police operation in Keysbrook, a rural outer suburb about 35 kilometres north-east of Mandurah and 70km south-east of the Perth CBD.

Members of the public had initially been advised to stay away from the area, but police have since confirmed there is no ongoing threat to public safety.

Aerial vision of the scene shows heavily armed police searching the large rural property, which appears to be an orchard.

There is a home and multiple tin sheds on the property, which is littered with scrap metal and old cars.

A woman is seen holding her hands in the air as she walks towards officers and speaks to them, before they continue their search.

At least seven police vehicles can be seen at the scene, while three St John ambulance crews have been placed on standby.

In a statement, police said the investigation remained ongoing.

"More information will be provided when available," police said in a statement.

"Significant resources" have been deployed to the area, they said.