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'ZNF184' 과발현 역이용, 암세포만 죽이는 정밀 의료 초석 마련
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Science·6/17/2026AI summary

'ZNF184' 과발현 역이용, 암세포만 죽이는 정밀 의료 초석 마련

UNIST·삼성병원·부산대 연구진이 급성림프모구백혈병 환자의 유전체 데이터를 분석하여, ZNF184 유전자가 암세포 DNA 복구 시스템을 마비시켜 질병을 악화시킨다는 사실을 규명했다. ZNF184 과발현 특성을 역이용하면 암세포만 골라 죽이는 합성치사 전략을 통해 정밀 의료의 초석을 마련할 수 있다.

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