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Steady4 stories4 sourcesLast updated: 6/9/2026

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The Two-Headed Dog: Vladimir Demikhov's Pioneering and Controversial Transplant Experiments
Science
5/1/2026AI summary

The Two-Headed Dog: Vladimir Demikhov's Pioneering and Controversial Transplant Experiments

This article examines Vladimir Demikhov, a Soviet surgeon who conducted controversial two-headed dog experiments between 1954 and the early 1960s, grafting the head and upper body of smaller dogs onto larger hosts. While most animals survived only days, Demikhov also performed pioneering heart and lung transplants (1946), orthotopic heart transplants (1951), and coronary artery bypass surgery (1953). His work influenced Christiaan Barnard's 1967 human heart transplant, though he received little recognition during his lifetime, only becoming a professor in 1998, the year he died at 82.

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TOI World
Chinese Scientists Develop Gene Therapy CS-101 Curing Five Beta-Thalassaemia Patients
Developing
Science·4/28/2026AI summary

Chinese Scientists Develop Gene Therapy CS-101 Curing Five Beta-Thalassaemia Patients

Scientists at ShanghaiTech University have developed CS-101, a base-editing gene therapy that successfully cured five Chinese patients with beta-thalassaemia. The treatment restored haematopoietic function, raising total haemoglobin and fetal haemoglobin levels, freeing patients from lifelong blood transfusions. China has 30 million thalassaemia gene carriers while the global total reaches 350 million.

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SCMP Economy