Consecutive miscarriages may stem from autoimmune issues, and doctors recommend early evaluation

2026/10/05 10:12

Dr. Li Mengru specially reminds women that if they experience more than two consecutive miscarriages, they should not ignore them and actively evaluate whether they have autoimmune problems. (Provided by the Affiliated Hospital of Hsinchu University of Traditional Chinese Medicine)

[Reporter Liao Xueru/Report from Hsinchu] "Why is this happening again?" Xiaofang (pseudonym), who is only 30 years old, has been pregnant three times in the past, but she miscarried despite high expectations. The physical torture coupled with repeated despair caused a huge blow to her soul. In order to find out the truth, she consulted Li Mengru, director of the Reproductive Medicine Center of China Medical University Hsinchu Hospital. After precise blood tests, she finally revealed the culprit of the consecutive miscarriages - it turned out that she was an "immune mother."

Li Mengru explained that some women have abnormal autoimmune antibodies in their bodies that mistakenly regard the embryo as a foreign body and attack it. The most common immune diseases include systemic lupus erythematosus and antiphospholipid syndrome. If the antibodies attack the thyroid gland, resulting in insufficient secretion of thyroxine, the embryo will not develop normally; if it attacks the endothelium of blood vessels, it will easily cause blood clots and block the nutrient supply to the placenta, eventually causing the embryo to stop growing.

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After finding the cause, the medical team tailored a treatment plan for her. When Xiaofang became pregnant successfully for the fourth time, her doctor arranged for her to take aspirin regularly to prevent blood clots and stabilize blood circulation. Under the precise medication and close monitoring across departments, the fetus grew steadily. Now she finally got rid of the haze of miscarriage and successfully gave birth to a healthy baby girl.

Li Mengru pointed out that the clinical medication used by immune mothers is quite diverse. In addition to aspirin, oral medications such as quinine or steroids are often used to control the immune response. If the condition is more complicated, a rheumatologist will be consulted to further evaluate the use of immune globulin or immunosuppressive injections. If you still cannot conceive naturally after medication, you may also be evaluated for combined IVF treatment.

Doctors specifically remind women that if they experience more than two consecutive miscarriages, they should not ignore them and actively evaluate whether they have autoimmune problems. The post-abortion care process is time-consuming and time-consuming. Only by identifying the cause early and continuously consulting with the rheumatology and immunology department to adjust medication during pregnancy can we effectively reduce the risk of miscarriage and greatly increase the chance of successfully delivering a live baby at full term.