
新竹附設醫院生殖醫學中心主任李孟儒指出,女性若經歷連續2次以上流產,應評估是否有自身免疫抗體問題,如系統性紅斑性狼瘡或抗磷脂症候群,並透過藥物治療與跨科會診可提升成功孕率。
AI-generated summary
連續流產可能受自身免疫抗體影響,常見疾病包括系統性紅斑性狼瘡及抗磷脂症候群,抗體可能攻擊甲狀腺或血管內皮,導致胚胎發育異常或營養供應中斷。
2026/10/05 10:12
李孟儒醫師特別提醒,女性若經歷連續2次以上流產,切莫輕忽,應主動評估是否有自體免疫方面問題。(中醫大新竹附醫提供)
〔記者廖雪茹/新竹報導〕「為什麼又是這樣?」年僅30歲的小芳(化名)過去曾歷經3次懷孕,卻都在滿懷期待中不幸流產。身體的折磨加上一次次的絕望,對她的心靈造成極大打擊。為了找出真相,她求診中國醫藥大學新竹附設醫院生殖醫學中心主任李孟儒,經過精密的抽血檢查,終於揭開連續流產的元兇—原來她是一位「免疫媽媽」。
李孟儒解釋,部分女性體內存在異常的自體免疫抗體,會誤將胚胎視為外來異物進行攻擊。其中最常見的免疫疾病包括系統性紅斑性狼瘡及抗磷脂症候群。若抗體攻擊甲狀腺,導致甲狀腺素分泌不足,胚胎便無法正常發育;若攻擊血管內皮,則容易引發血栓,阻斷胎盤的營養供應,最終導致胚胎停止生長。
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找到病因後,醫療團隊為她量身打造治療計畫。當小芳第四次順利懷孕時,醫師安排她定期服用阿斯匹靈以預防血栓、穩定血液循環。在跨科別的精準用藥與密切監控下,胎兒一路穩定成長,如今她終於擺脫流產陰霾,順利產下一名健康的寶貝女嬰。
李孟儒指出,免疫媽媽的臨床用藥相當多元,除了阿斯匹靈,常搭配奎寧或類固醇等口服藥物來控制免疫反應。若狀況較為複雜,則會會診風濕免疫科醫師,進一步評估使用免疫球蛋白或免疫抑制針劑。若經藥物調理後仍無法自然受孕,也可評估結合試管嬰兒療程。
醫師特別提醒,女性若經歷連續2次以上流產,切莫輕忽,應主動評估是否有自體免疫方面問題。流產後的調養過程曠日廢時,及早釐清原因並在孕期持續會診風濕免疫科調整用藥,才能有效降低流產風險,大幅提升順利足月產下活產寶寶的機會。
AI outlook — possibilities, not facts
未來更多反覆流產案例將被納入自身免疫篩檢標準流程
Likely · Within months

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