Fantasy football Week 10 PPR cheat sheet: Should you start Josh Downs in his first game with Patrick Mahomes?

Every lineup decision matters as the Fantasy football season approaches its midpoint, and Week 10 presents another challenging slate for managers trying to separate dependable starters from potential disappointments. With several teams on bye, injuries continuing to shake up depth charts and several big-name players facing difficult matchups, knowing who to trust could be the difference between securing a much-needed victory and watching valuable Fantasy points pile up on your bench.

That's where Dave Richard's Week 10 PPR cheat sheet comes in.

What do the numbers mean? All weekly analysis, from data points to matchup outlooks to game-flow predictions, is represented as a number on a 1-10 confidence scale. The higher the number next to a player's name, the more confident I am that you should start him. The numbers are not projections but confidence scores to help you pick who to start. All relevant players for this week are listed, so if you do not see a player's name, do not start him.

To find a specific player, use your search function (CTRL-F on PCs and Command-F on Macs). If neither is an option, or if you're on a mobile device, you can search by typing the name in the URL bar or scrolling down by game. If you're still unsure, just send Dave a note (@DaveRichard), and he will take a look, time permitting. Remember to use the #AskFFT hashtag!

If you're reading this on Sunday, please refer to CBS Sports' weekly rankings, which are updated in real-time.

Ready to get off on the right foot? Here's how to approach every play for this week in every PPR league.

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

CommandersGiantsJayden Daniels6.1J.J. McCarthy4.4Rachaad White5.26Cam Skattebo6.65Austin Ekeler2.92Devin Singletary2.88Stefon Diggs5.4Malik Nabers8.4Antonio Williams4.72Malachi Fields3.48Treylon Burks4.35Darnell Mooney2.0Chigoziem Okonkwo5.04Isaiah Likely6.5Commanders DST5.4Giants DST7.3

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

PatriotsLionsDrake Maye8.2Jared Goff7.4Corey Kiner5.22Jahmyr Gibbs9.8Lan Larison2.4Amon-Ra St. Brown8.2Demario Douglas6.55Jameson Williams7.1Mack Hollins5.1Sam LaPorta5.14Efton Chism III3.98Lions DST6.1Hunter Henry5.42Eli Raridon3.24Patriots DST4.9

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

ChiefsFalconsPatrick Mahomes7.1Michael Penix Jr.5.6Kenneth Walker III9.85Bijan Robinson9.6Emmett Johnson2.98Drake London7.38Rashee Rice6.95Jahan Dotson3.72Josh Downs4.46Kyle Pitts5.02Xavier Worthy3.12Falcons DST2.8Travis Kelce5.58Chiefs DST7.6

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

TexansBrownsC.J. Stroud7.3Deshaun Watson4.2Woody Marks5.24Quinshon Judkins5.0Nico Collins6.9Dylan Sampson4.66Tank Dell5.38Denzel Boston5.6Xavier Hutchinson5.36KC Concepcion5.34Kayshon Boutte3.62Harold Fannin Jr.5.45Marvin Harrison Jr.3.1Browns DST5.6Dalton Schultz3.68Texans DST8.6

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

VikingsPackersKirk Cousins6.1Jordan Love7.6Aaron Jones4.42Kaleb Johnson3.55Jordan Mason4.18Pierre Strong Jr.3.32Justin Jefferson7.22MarShawn Lloyd2.9Jordan Addison4.64Christian Watson8.3T.J. Hockenson6.62Matthew Golden8.12Vikings DST7.4Savion Williams3.6Tucker Kraft5.48Packers DST7.5

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

DolphinsColtsKyle McCord3.4Daniel Jones4.7Ollie Gordon6.28Jonathan Taylor8.7Caleb Douglas5.28Seth McGowan3.34Malik Washington4.58Ashton Dulin3.85Greg Dulcich3.7Deion Burks2.02Dolphins DST5.3Tyler Warren6.68Colts DST6.3

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

PanthersSaintsBryce Young7.0Tyler Shough6.9Chuba Hubbard8.65Audric Estime5.25Tetairoa McMillan7.02Alvin Kamara3.44Jalen Coker6.22Chris Olave7.9Darren Waller5.06Jordyn Tyson5.12Tommy Tremble3.58Devaughn Vele4.08Panthers DST4.8Juwan Johnson4.52Saints DST4.2

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

BillsJetsJosh Allen8.9Geno Smith6.0James Cook9.1Breece Hall6.85Ty Johnson2.16Braelon Allen4.82Ray Davis1.8Garrett Wilson6.92DJ Moore6.7Adonai Mitchell5.48Khalil Shakir4.05Omar Cooper Jr.5.18Keon Coleman3.26Mason Taylor3.38Dalton Kincaid5.2Kenyon Sadiq2.52Bills DST7.7Jets DST2.7

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

JaguarsTitansTrevor Lawrence8.0Cam Ward5.7Bhayshul Tuten7.3Tony Pollard6.15Chris Rodriguez Jr.4.3Michael Carter2.12Parker Washington7.15Carnell Tate6.82Jakobi Meyers4.95Wan'Dale Robinson4.98Brian Thomas Jr.2.64Elic Ayomanor3.8Brenton Strange4.7Chimere Dike2.55Jaguars DST9.1Gunnar Helm3.42Titans DST3.4

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

RamsCardinalsMatthew Stafford5.5Carson Beck2.2Kyren Williams7.5Tyler Allgeier4.78Blake Corum6.4Devin Duvernay2.38Tutu Atwell4.68Trey McBride6.88Konata Mumpfield4.6Cardinals DST4.3Tyler Higbee4.5Colby Parkinson3.74Rams DST9.4

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

SeahawksRaidersDrew Lock3.7Fernando Mendoza4.3Zach Charbonnet6.75Ashton Jeanty5.62Jadarian Price5.16Mike Washington Jr.2.44Jaxon Smith-Njigba9.3Tre Tucker5.08Cooper Kupp3.28Brock Bowers8.1AJ Barner2.3Michael Mayer4.74Seahawks DST9.2Raiders DST3.2

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

49ersCowboysBrock Purdy8.1Dak Prescott7.5Christian McCaffrey9.7Javonte Williams8.0Kaelon Black3.36CeeDee Lamb9.25Keenan Allen4.8Ryan Flournoy5.52Jordan Watkins4.62Brevyn Spann-Ford2.5Demarcus Robinson3.88Cowboys DST2.9George Kittle7.1249ers DST7.0

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

SteelersBengalsAaron Rodgers6.1Joe Burrow9.3Jaylen Warren8.6Chase Brown7.0Rico Dowdle4.85Samaje Perine2.28Germie Bernard5.55Ja'Marr Chase9.4DK Metcalf5.5Tee Higgins9.0Darnell Washington4.32Dohnte Meyers3.52Pat Freiermuth3.76Mike Gesicki4.02Steelers DST5.2Bengals DST5.0

Start 'em

10.0-7.00

6.99 - 5.01

5.00 - 0

Sit 'em

ChargersRavensJustin Herbert4.0Jacoby Brissett5.8Omarion Hampton4.55Derrick Henry7.45Keaton Mitchell2.95Justice Hill3.5Quentin Johnston3.78Zay Flowers7.25Oronde Gadsden II3.65Rashod Bateman3.15Chargers DST4.0Mark Andrews4.1Josh Cuevas2.38Ravens DST8.0