'Very dangerous' unapproved peptide explosion hits NSW hospitals

A surge in hospitalisations related to the use of unapproved peptides promoted as "wellness" products has prompted a warning from NSW health authorities.

New data from NSW Health shows 1,180 people turned up to hospital emergency departments across the state between July last year and September this year seeking medical treatment after taking unapproved peptides.

Monthly hospital presentations increased from just 5 in July 2025 to almost 220 last month.

Peptides are short chains of amino acids that make up proteins in our bodies and there are a number of peptide-based medicines that are approved by the Therapeutic Goods Administration (TGA).

But unregulated peptides have exploded in popularity on social media, with promises of weight loss, aging reversal and muscle growth.

Health Minister Ryan Park said such unapproved peptides could have serious side effects, including liver and kidney damage, allergic reactions, severe vomiting and other complications.

"People present to the emergency departments quite unwell and people need treatment, so this is not minor," he said.

"People can get very unwell, very quickly as a result of these products.

'Very dangerous'

NSW Health said products that were not approved may contain peptides, including BPC-157, GHK-Cu, TB-500, retatrutide and CJC-1295.

Mr Park said people should not buy or use unapproved products, particularly those promoted through social media and online retailers.

"I think it'll be a topic for conversation with health ministers over the next few months, simply because of the scale of increase of use across the community and the potential harms that it has on individuals."

People are being urged to talk with their usual doctor about their health goals and only use approved peptide products that have been prescribed by a qualified health practitioner in Australia.

Those already using an unprescribed peptide product are being urged to speak with a health professional before taking the next dose to ensure it is a registered medicine.

"If you haven't had a product prescribed by a GP and you haven't had it issued at a pharmacy, please don't use it," Mr Park said.