Zuffa Boxing 12 start time, fight card, predictions and where to watch Chris Billam Smith vs. Cheavon Clarke

Zuffa Boxing returns on Saturday with the upstart promotion's 12th numbered event. In the main event from Copper Box Arena in London, Chris Billam-Smith will take on Cheavon "C4" Clarke in an intriguing cruiserweight bout.

Both Billam-Smith and Clarke were successful in exciting Zuffa debuts, though in very different ways.

Billam-Smith, the former WBO cruiserweight champion, made his Zuffa debut against Ryan Rozicki in June. Billam-Smith looked tremendous throughout the fight, putting heaps of punishment on Rozicki, though Rozicki gained respect from the larger boxing world for showing an iron chin and loads of heart.

Eventually, Billam-Smith's attack was too much and Rozicki's corner stopped their fighter from taking any further punishment after seven rounds of action. It was a big statement for Billam-Smith, a well-known, talented fighter who decided to show he was willing to stand and trade in a style that gave Rozicki his only hope of victory.

While Billam-Smith's win was hard-fought but one-sided, Clarke had to battle back from significant adversity on the same card.

Clarke was facing Jack Massey when Massey scored two knockdowns in the fourth round of their bout. With things looking particularly dire, Clarke managed to turn things around, scoring his own knockdown in the seventh round and forcing the referee to stop the bout.

The win was Clarke's second since suffering back-to-back defeats to Leonardo Mosquea and Viddal Riley.

Zuffa Boxing 12 also features some other compelling fights with familiar names, including the return of Shane Mosley Jr. for the first time since his impressive win over Serhii Bohachuk when he faces Denzel Bentley in middleweight action, and a preliminary light heavyweight bout between Zach Parker and Umar Dzambekov.

Let's take a look at the complete card for Saturday night with the latest odds from DraftKings before getting to a prediction and expert pick on the main event below.

Zuffa Boxing 12 fight card, odds

Chris Billam-Smith -450 vs. Cheavon Clarke +320, cruiserweights

Denzel Bentley -160 vs. Shane Mosley Jr. +125, middleweights

Sam Hickey -2000 vs. Amaury Massenaux +900, middleweights

Kayla Allen -1400 vs. Julia Igel +750, junior welterweights

Lucas Roehrig -2000 vs. Connal McDonald +900, cruiserweights

Umar Dzambekov -330 vs. Zach Parker +250, light heavyweights

Vinnie Kemp vs. Liam McElhinney, middleweights

Masood Abdulah -260 vs. Adan Palma +200, featherweights

Where to watch Zuffa Boxing 12

Date: Nov. 6 | Location: Copper Box Arena -- London

Prelims begin at 12:15 p.m. ET

Main card begins at 2 p.m. ET

Watch live: Paramount+ (subscribe now for as little as $8.99 per month)

Prediction

Billam-Smith has been to the top of the sport, holding a legitimate world championship and making multiple successful defenses. He's not a perfect boxer, but he's a skilled one who has shown that he can box or slug when the fight calls for it. Billam-Smith knows that standing and trading gives Clarke his best (and maybe only) path to victory, but that didn't stop Billam-Smith from doing the same against Rozicki.

Still, the reality is that Clarke needs Billam-Smith to make some bad decisions and leave big openings for him to win. Clarke has power and he did pick himself up off the canvas twice in his most recent win, but Billam-Smith is a far better fighter than Massey. Billam-Smith is also considerably better than Mosquea and Riley, both of whom beat Clarke on the scorecards.