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Back血癌14年兩度復發 49歲婦接受兒子半相合幹細胞移植重生
血癌14年兩度復發 49歲婦接受兒子半相合幹細胞移植重生
Health
自由时报4 hours agoHealth4 min readChinaView translation

血癌14年兩度復發 49歲婦接受兒子半相合幹細胞移植重生

49歲洪小姐14年前確診急性骨髓性白血病,歷經兩次復發,先後接受姊姊與兒子捐贈造血幹細胞,目前病況穩定定期追蹤。

Quick Look

49歲洪小姐14年前罹患急性骨髓性白血病,歷經兩度復發,分別接受姊姊全相合與兒子半相合造血幹細胞移植,目前病況穩定。台中榮總醫師指出10年後復發少見,並強調個管師在治療與心理支持的重要角色。

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Why It Matters

急性白血病是造血系統惡性腫瘤,台灣每年約950至1000人罹病,主要與基因突變、染色體異常有關。

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49歲洪小姐14年前確診急性骨髓性白血病(俗稱血癌),經化療後完全緩解,3年後復發,接受姊姊造血幹細胞移植,沒想到10年後竟二度復發,非常少見,今年接受兒子捐贈骨髓,目前病況穩定,定期追蹤,洪小姐感謝家人支持,今天與姊姊、丈夫回院感謝醫療團隊。

台中榮總血液腫瘤科主任陳聰智指出,急性白血病是造血系統惡性腫瘤,因未成熟白血球異常增生、排擠正常血球所致,台灣每年約950至1000人罹病,病因複雜,主要與基因突變、染色體異常有關,少數與長期化學物質或輻射暴露有關。

血癌復發則與化療後殘留病灶、移植免疫細胞弱化、癌細胞突變和病人基因都有關,治療後2年復發比例有30-40%,隨著追蹤時間越長,復發風險越小,但10年後復發很少見,機率小於5-10%。

洪小姐14年前突然暈倒,輾轉就醫確診罹患急性骨髓性白血病,接受2次化療後完全緩解,3年後復發,接受姊姊的全相合造血幹細胞移植,並按期追蹤,去年丈夫覺得她臉色蒼白,親友也發現她臉色不好,自己也覺得運動後會頭暈,回診確認血癌復發。

洪小姐去年10月追蹤發現二度復發,讓她非常震驚、難過,這次比對出兒子骨髓半吻合,接受半相合幹細胞移植重生。

陳聰智說,血癌常見症狀包含紅血球不足導致臉色蒼白、頭暈、疲倦;白血球功能異常引發持續發燒、反覆感染;血小板低下造成瘀青、紫斑、出血;以及骨頭痠痛、淋巴結腫大,應儘速就醫,把握治療黃金期。

血腫科個管師鍾欣樺說,白血病打斷病人生活,加上移植配對、治療細節繁瑣,移植後初期又須嚴格防感染、關注排斥症狀,同時面對家庭經濟負擔,草木皆兵的心情常伴隨憂慮、失眠等壓力反應,個管師除安排治療,也需轉介生活輔助資源,陪病人走過治療與身心調適的每一步。

中榮血液腫瘤科在滕傑林前科主任及院方支持下,2023年由專科護理師團隊創建官方即時通訊帳號,適逢新冠疫情解封,協助病友安排新冠抗病毒藥物和血癌標靶藥物治療時程、留意併發症等,安心抗癌又抗疫;2024年繼台大醫院後,中榮設置「造血幹細胞移植個案管理師」專責職缺;2025年正式導入專責服務,全面提升移植照護品質,目前已照護59位自體、49位異體移植病人,並協助超過100人次周邊血液幹細胞收集。

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  • 兒子捐贈幹細胞後的長期追蹤情況如何?

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