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Back哪種睡眠讓失智風險降46%? 9.5萬人研究揭護腦關鍵
哪種睡眠讓失智風險降46%? 9.5萬人研究揭護腦關鍵
Health
自由时报5 hours agoHealth2 min readChinaView translation

哪種睡眠讓失智風險降46%? 9.5萬人研究揭護腦關鍵

Quick Look

一項涵蓋9萬5559名成年人的研究發現,快速動眼期(REM)睡眠時間較長者與失智症、帕金森氏症及心臟衰竭等83種疾病風險較低存在顯著關聯;但研究為觀察性質,未證明延長REM睡眠可直接預防疾病。

AI-generated summary

Why It Matters

睡眠結構階段對長期健康的影響正受到科學關注,快速動眼期(REM)睡眠與認知及神經退化性疾病的關聯性是研究熱點。

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2026/10/14 11:33

眠品質不只看時間長短,快速動眼期也可能與失智症及帕金森氏症等疾病風險有關;情境照。(圖取自 Freepik)

〔編譯陳成良/綜合報導〕睡眠不僅關乎時間長短,睡眠時經歷的結構階段,更可能深刻影響長期健康。一項涵蓋9萬5559名成年人的大型醫學研究發現,快速動眼期(REM)睡眠時間較長者,與失智症、帕金森氏症及心臟衰竭等83種疾病風險較低存在顯著關聯。不過研究團隊強調,這項成果屬於觀察性研究,並未證明延長快速動眼期睡眠就能直接預防疾病。

據福斯新聞數位網(Fox News Digital)報導,這項研究9月17日發表於醫學期刊《PLOS Medicine》。研究團隊分析英國生物樣本庫(UK Biobank)參與者數據,受試者連續7天配戴腕式加速度計,研究人員利用深度學習演算法分析睡眠階段與規律性,並追蹤健康紀錄中位數達8.9年,評估睡眠指標與1049種健康結果的關聯性。

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研究結果顯示,每晚快速動眼期睡眠較長者,在追蹤期間與帕金森氏症風險估計值低約80%、失智症低46%及心臟衰竭低26%相關。深層睡眠較長則與第2型糖尿病、重度憂鬱症等7種疾病風險較低有關。不過研究指出,兩種睡眠階段對應的健康效益範圍不同,無法直接認定快速動眼期比深層睡眠更為重要。

每晚6至8小時罹病機率最低

在睡眠總時數方面,研究發現每晚睡6至8小時者,與69種疾病呈現最低風險關聯;相對地,每晚睡眠少於5小時,則與37種疾病風險增加相關。此外,睡眠規律性較差、入睡後頻繁醒來,也與部分精神及焦慮風險上升有關。

未參與研究的外部醫學專家提醒,神經退化性疾病或心臟衰竭在臨床確診前數年,大腦病理變化就可能已開始干擾睡眠機制,因此睡眠異常不見得是致病原因,更可能是疾病早期的隱性警訊,兩者之間恐存在雙向交互影響。

研究團隊補充,腕式裝置判讀睡眠階段的精確度仍不及臨床多項睡眠生理檢查,且受試者多來自英國單一資料庫,結論未必能直接套用至所有族群。研究主要提供預防醫學參考,若民眾長期面臨嚴重睡眠障礙或日間持續嗜睡,仍應尋求專業醫療團隊進行臨床評估。

What to Watch

AI outlook — possibilities, not facts

  • 未來將有更多臨床試驗探索透過行為或藥物干預延長快速動眼期睡眠對預防失智症的潛在效果

    Possible · Within months

Open Questions

  • 快速動眼期睡眠延長是否能直接降低失智症或帕金森氏症發生率?
  • 該研究結果是否適用於非英國族群或不同年齡層?
  • 腕式加速度計監測睡眠階段的準確度與臨床多項睡眠生理檢查相比有何差距?

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