
SportsLine daily fantasy expert Mike McClure has released his top NFL DFS picks for the Week 5 Monday Night Football matchup between the Los Angeles Rams and Buffalo Bills, highlighting quarterback Josh Allen and running back Blake Corum as key selections while emphasizing the importance of finding undervalued players to maximize lineup potential on FanDuel and DraftKings.
AI-generated summary
The Los Angeles Rams lead the NFL in total offense but rank in the bottom 10 in points per game, while the Buffalo Bills rank seventh in total offense and second in points per game heading into their Week 5 Monday Night Football matchup.
Two of the top offenses in the league meet on 'Monday Night Football' to close out the Week 5 NFL schedule as the Los Angeles Rams host the Buffalo Bills at 8:15 p.m. ET in the game with the highest over/under (55.5) on the board in Week 5. The Rams lead the NFL in total offense at 417 yards per game, though that hasn't translated well to scoring as they are in the bottom 10 in the NFL in points per game. Buffalo, meanwhile, ranks seventh in total offense, and second in points per game, so those are all data points to consider when building NFL DFS lineups for contests such as the $475k NFL Monday Night Special on FanDuel or the $1.5M Monday Night Showdown GPP on DraftKings.
Big names like Josh Allen, Kyren Williams, Puka Nacua, James Cook, Davante Adams and Matthew Stafford are among the top possible NFL DFS picks, but who are the best values in the NFL DFS player pool among both the stars and the role players? Before making any 'Monday Night Football' NFL DFS picks on sites like FanDuel or DraftKings, be sure to check out the NFL DFS advice, strategy, and stacks from SportsLine daily Fantasy expert Mike McClure.
McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including finishing tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him could be way up.
Now, McClure has turned his attention to Rams vs. Bills on 'MNF' and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.
Top NFL DFS picks for Week 5, Bills vs. Rams
One of McClure's top NFL DFS picks for Bills vs. Rams on 'MNF' is Buffalo quarterback Josh Allen. One of the top daily and season-long Fantasy options for the past several years, Allen brings both a high floor and a high ceiling since he's extremely effective as a passer and a rusher. He has seven rushing touchdowns on the season and is averaging a little more than 250 passing yards per game. Allen has been particularly strong against the Rams in his career, piling up 10 passing touchdowns and five rushing scores in three career matchups.
McClure's also building around Rams running back Blake Corum in a bit of a contrarian play. The third-year back out of Michigan has been largely effective when called upon this season, averaging nearly 5.0 yards per carry. He's been quiet the past couple weeks, but he had double-digit carries in both Week 1 and Week 2. In a game with this many stars and projected points, it's important to find some cheaper options to free up cap space, and McClure is banking on Corum outperforming his relatively low expectations. See who else to roster at SportsLine.
How to set Week 5 NFL DFS 'Monday Night Football' lineups
McClure is targeting another undervalued player who could go off for huge numbers on Monday. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure's NFL DFS picks, at SportsLine.
AI outlook — possibilities, not facts
Josh Allen will have a strong performance against the Rams based on his historical success in matchups
Likely · Within hours
Blake Corum will outperform his low expectations as a contrarian DFS pick
Possible · Within hours

SEC presidents voted to adopt standardized NIL and revenue-share contracts across the league, effective immediately, allowing schools to share up to $21.6 million with athletes this academic year. The move follows the Big Ten's lead and aims to strengthen self-governance amid ongoing legal and regulatory challenges, including House v. NCAA settlement compliance and anticipated antitrust protections under the Protect College Sports Act.

BetMGM promotes bonus code CBSSPORTS offering new users up to $1,500 in bonus bets alongside SportsLine projections favoring the Bills to cover as 3.5-point underdogs against the Rams in Monday Night Football, with specific player props on Josh Allen's passing yards and Keon Coleman's longest reception.

FanDuel offers new users $250 in bonus bets for wagering $5+ over five days ahead of the NFL Week 5 Bills vs. Rams game, where the Rams are 3.5-point favorites and the Over/Under is 54.5. The SportsLine Projection Model recommends betting the Under 54.5 total and Josh Allen Under 244.5 passing yards, citing Allen's projected 195.6 passing yards and concerns over Buffalo's receiving corps. The model has returned over $7,000 for $100 players since inception and was on a 55-44 run entering Week 5 of the 2026 NFL season.

FanDuel offers new users $250 in bonus bets for wagering $5+ over five days, with featured bets on the Bills vs. Rams Under 54.5 and Dodgers vs. Brewers Over 6.5, supported by SportsLine Projection Model simulations showing strong historical returns and specific game insights for Monday, Oct. 12.

The SportsLine Projection Model favors the Buffalo Bills to cover as 3.5-point underdogs against the Los Angeles Rams in Week 5 of the 2026 NFL season, also projecting value in the Under 55.5 total points and a player prop on Keon Coleman's longest reception, with promotional offers from DraftKings highlighted throughout.

The Cleveland Guardians and Tampa Bay Rays face off in the ALCS starting Monday in St. Petersburg, with the winner advancing to the World Series as an underdog against the Dodgers or Brewers. Tampa Bay is favored at -169 on the moneyline, with Drew Rasmussen set to start Game 1 for the Rays and Foster Griffin for Cleveland. The article highlights betting odds, historical context including the Junior Caminero trade, and postseason history between the teams.