
The SportsLine Projection Model favors the Buffalo Bills to cover as 3.5-point underdogs against the Los Angeles Rams in Week 5 of the 2026 NFL season, also projecting value in the Under 55.5 total points and a player prop on Keon Coleman's longest reception, with promotional offers from DraftKings highlighted throughout.
AI-generated summary
The SportsLine Projection Model has simulated every NFL game 10,000 times and has been up over $7,000 for $100 players on top-rated NFL picks since its inception, entering Week 5 of the 2026 season on a 55-44 run dating back to 2024.
The Week 5 NFL slate concludes with a potential Super Bowl Preview in Bills vs. Rams, an elite contest to claim on the newest DraftKings promo code, which gives new users $200 in bonus bets and three months of free NBA League Pass after making a $5 bet, paid within 21 days. The Bills are 3-1, while the Rams are 2-2 behind two top NFL offenses. The SportsLine Projection Model is backing the Bills to cover as 3.5-point underdogs as part of its Bills vs. Rams best bets at DraftKings. The model also sees value in Under 55.5 total points, and SportsLine expert Megan Shoup has locked in her top player prop betting pick for Rams vs. Bills NFL best bets at DraftKings. Bills wide receiver Joshua Palmer (shoulder) is inactive. Claim the latest DraftKings promo code, where new users get $200 in bonus bets + free NBA League Pass after making a $5 wager:
Check out our DraftKings promo code review for full details about one of our best sports betting apps.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model entered Week 5 of the 2026 NFL season on a 55-44 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong returns.
Bills vs. Rams best bets at DraftKings
Bills +3.5 (-118)
Under 55.5 total points (-102)
Keon Coleman, Bills, Over 19.5 yards longest reception (-111)
Combining the three picks into a Monday Night Football same-game parlay betting pick at DraftKings would result in a payout of +495 (risk $100 to profit $495, odds subject to change). Claim $200 in bonus bets + three months of free NBA League Pass after your first $5 wager at DraftKings here:
Bills (+3.5)
The Bills opened their season 3-0 before a 29-26 loss to defending AFC champion New England last week. Buffalo has started its season against four teams that made the playoffs last season. Monday will make five, as it hasn't been an easy start. Still, the Bills have the No. 1 scoring offense at 31.8 points per game behind the elite play of quarterback Josh Allen. The Rams needed a late comeback to top the Eagles last week in a 24-20 win as they haven't been quite as dominant as many expected entering the season. The model projects the Bills to cover in 52% of simulations. Back the Bills at DraftKings here and claim $200 in bonus bets and free NBA League Pass after making a $5+ wager as a new user:
Under 55.5 total points
Yes, the Bills have the No. 1 scoring offense in the NFL, but the Rams have a loaded defense with players such as Aaron Donald and Trent McDuffie. Los Angeles has played one true home game this season, and in it, the Rams held the Giants to six points. The Rams have the No. 9 scoring defense at 20.8 points per game allowed, and their offense hasn't been quite as elite as many expected to start the season, ranking 19th in scoring at 21.3 ppg. The model projects the Under to hit in 63% of simulations. Back the Under at DraftKings here and claim $200 in bonus bets + free NBA League Pass after making a $5+ wager as a new user:
Keon Coleman, Bills, longest reception Over 19.5 yards
"Keon Coleman has gotten explosive plays the last three weeks with or without D.J. Moore in the lineup," SportsLine expert Megan Shoup said. "In a game that I think will be close and high-scoring, I like Josh Allen to take some intermediate to deep shots for Coleman. In the last three weeks, he has had long receptions of 22, 37, and 34 yards." Back this player prop at DraftKings here and claim $200 in bonus bets and free NBA League Pass after making a $5+ wager as a new user:
Want more Bills vs. Rams picks for Monday Night Football?
You've seen some of the model's and SportsLine team of experts' Monday best bets. Now, get against the spread, total and money-line picks for all games, including NFL, MLB, college football, NHL, and more, all from the SportsLine Projection Model, which has simulated every game 10,000 times.
Responsible Gaming at DraftKings
DraftKings provides a "Responsible Gaming Center" tab for users on their profile pages. This landing page includes help for problem gambling as well as "Safer Play Tools," a list of options that allow users to limit their use of the app with deposit limits (daily, weekly or monthly), wagering limits, max wager limits and time limits. The platform also has a support team available 24/7 via live chat, and provides contact information for state and national helplines for those who need additional help. If you think you may have a gambling problem, you can call or text 1-800-MY-RESET.
AI outlook — possibilities, not facts
Buffalo Bills will cover the 3.5-point spread against the Los Angeles Rams
Likely · Within days
Total points in Bills vs. Rams game will stay under 55.5
Likely · Within days
Keon Coleman will have a longest reception over 19.5 yards
Possible · Within days

The U.S. women's national soccer team prepares for a second friendly against Spain in Chester, Pennsylvania, seeking to demonstrate improvement after a 2-0 loss in the first match, with head coach Emma Hayes emphasizing execution and structural consistency as the World Cup approaches in eight months.

SEC presidents voted to adopt standardized NIL and revenue-share contracts across the league, effective immediately, allowing schools to share up to $21.6 million with athletes this academic year. The move follows the Big Ten's lead and aims to strengthen self-governance amid ongoing legal and regulatory challenges, including House v. NCAA settlement compliance and anticipated antitrust protections under the Protect College Sports Act.

BetMGM promotes bonus code CBSSPORTS offering new users up to $1,500 in bonus bets alongside SportsLine projections favoring the Bills to cover as 3.5-point underdogs against the Rams in Monday Night Football, with specific player props on Josh Allen's passing yards and Keon Coleman's longest reception.

FanDuel offers new users $250 in bonus bets for wagering $5+ over five days ahead of the NFL Week 5 Bills vs. Rams game, where the Rams are 3.5-point favorites and the Over/Under is 54.5. The SportsLine Projection Model recommends betting the Under 54.5 total and Josh Allen Under 244.5 passing yards, citing Allen's projected 195.6 passing yards and concerns over Buffalo's receiving corps. The model has returned over $7,000 for $100 players since inception and was on a 55-44 run entering Week 5 of the 2026 NFL season.

FanDuel offers new users $250 in bonus bets for wagering $5+ over five days, with featured bets on the Bills vs. Rams Under 54.5 and Dodgers vs. Brewers Over 6.5, supported by SportsLine Projection Model simulations showing strong historical returns and specific game insights for Monday, Oct. 12.

The Cleveland Guardians and Tampa Bay Rays face off in the ALCS starting Monday in St. Petersburg, with the winner advancing to the World Series as an underdog against the Dodgers or Brewers. Tampa Bay is favored at -169 on the moneyline, with Drew Rasmussen set to start Game 1 for the Rays and Foster Griffin for Cleveland. The article highlights betting odds, historical context including the Junior Caminero trade, and postseason history between the teams.