
Karl Deisseroth, Peter Hegemann and Georg Nagel honored for work on optogenetics and light-gated ion channels.
The Nobel Prize in medicine was awarded to Karl Deisseroth, Peter Hegemann, and Georg Nagel for their research into light-gated ion channels and optogenetics, kicking off Nobels week in Stockholm.
AI-generated summary
The Nobel Prize in medicine is awarded annually for significant discoveries in the life sciences or medicine, kicking off the Nobel Prize announcements in October.
STOCKHOLM — The Nobel Prize in medicine was awarded Monday to three scientists working on the mechanisms the brain uses to switch on, or off, the activity of individual nerve cells.
Karl Deisseroth, 54, Peter Hegemann, 71, and Georg Nagel, 73, have carried out research into light-gated ion channels and optogenetics. They are based at universities in Germany and the United States.
The Nobel committee lauded their work, writing on X that the method "is now being used in laboratories around the world to reveal the brain's mysteries."
The Nobel Assembly said Deisseroth is based at Stanford University in California, while Hegemann is at Humboldt University in Berlin and Nagel at the University of Würzburg in Germany.
Thomas Perlmann, the secretary of the medicine committee, said he was able to reach all three winners by phone Monday.
The prize was announced at the Karolinska Institute in Stockholm, kicking off Nobels week.
The prize money this year is 12 million Swedish kronor (about $1.2 million).
Last year, the prize went to three scientists researching the immune system.
Monday's medicine prize is followed by the physics prize on Tuesday, chemistry on Wednesday and literature on Thursday.
After Friday's peace prize is awarded, the Nobel Memorial Prize in Economic Sciences will be announced on Oct. 12.
The prize money this year is 12 million Swedish kronor (about $1.2 million), whether for an individual, small group of laureates or organization.
AI outlook — possibilities, not facts
Physics, chemistry, and other Nobel prizes will be announced during the week.
Very likely · Within days

This month’s science roundup covers a potential dark matter signal from the LUX-ZEPLIN detector in South Dakota, observed entanglement of Z bosons at the LHC’s ATLAS experiment, a yeast-and-gelatin-based material for 3D-printing Martian habitats, evidence of betel nut use for psychoactive effects in Late Pleistocene humans in Indonesia, a newly discovered 17th-century manuscript describing a four-lens telescope possibly made by Galileo, and the historical use of cosmoramas as 19th-century virtual home tours in Britain and Ireland.

A powerful El Niño climate pattern is influencing global weather, but NOAA faces staff cuts and budget uncertainty under the Trump administration, leading to a scaled-back research response compared to 2015-16.

A RIKEN study reveals that fruit flies store 'nutritional memory' of larval protein intake via the Lsp2 protein. Low-protein diets in larvae reduce Lsp2 levels, leading to slower protein production in adulthood and extended lifespans, though human application remains speculative.
Canadian researchers identified two new sea spider species in the Salish Sea between Washington State and British Columbia, marking the first discovery in the area in over 100 years. The species, Callipallene pilosuspedes and Tanystylum kiixin, were found off Vancouver and Quadra Islands and exhibit unique traits such as red eyes, ovigers for grooming, and parasitic feeding on hydroids.

Astronomers using the James Webb Space Telescope have observed that the rings of the minor body Chariklo have undergone significant changes, with one ring thickening and the other fading, suggesting active physical evolution in small Solar System objects.

A study in Science Advances suggests hunter-gatherers in ancient Indonesia used betel nuts for pain relief. Researchers identified unique tooth grooves in 25,000-year-old remains, matching chemical traces and physical wear patterns consistent with long-term nut-sucking.