Ultraprocessed foods linked to higher risk of chronic illness, depression, cancer and death
Quick Look
A new analysis of over 50 studies involving nearly 9 million adults finds that diets high in ultraprocessed foods significantly increase the risk of cardiovascular disease, diabetes, obesity, depression, anxiety, digestive diseases, cancer and all-cause mortality, with each 100-gram daily increase raising cancer risk by 4% and death risk by 3%.
AI-generated summary
Why It Matters
Ultraprocessed foods are defined as products made with sodium, added sugars, refined grains and industrial ingredients that enhance taste and texture, and are increasingly prevalent in modern diets, particularly in the United States where they make up about 60% of the average diet.
There’s now even more evidence that eating ultraprocessed foods is bad for your health.
A diet that has more cookies, chips, cakes, pizza, hot dogs and other salty and sweet goods – such as candy-filled grilled cheese sandwiches – can greatly raise your risk of chronic illness, a new analysis of more than 50 studies, including nearly 9 million adults, reveals.
An ultra-processed-heavy diet increased the risk of cardiovascular events, diabetes and obesity by nearly a quarter. It also raised the risk of depression and anxiety by 27 percent and suffering a digestive disease by 31 percent.
And every extra 100 grams of these foods a day elevated the risk of developing cancer by 4 percent, and the risk of death by any cause by 3 percent.
“In our modern society, our diet and food is maybe not safe … we should eat more vegetables and reduce the ultra-processed food to make us healthier,” Dr. Xiao Liu, lead author of the study and a physician at Sun Yat-Sen Memorial Hospital, told ABC News on Tuesday.
The researchers also noted that emerging evidence suggests combining additives in ultraprocessed foods could have a “cocktail effect” on human health, combining to create a stronger, toxic impact.
Past studies have shown that ultraprocessed foods affect the gut, promote inflammation tied to cancer and insulin resistance that leads to diabetes, the researchers said.
In addition, compounds that may form during food processing have been associated with a higher incidence of cardiovascular disease, they added.
How often people ate these foods was recorded in journals and questionnaires, though the researchers note that means their assessment relies on subjective information.
Some 60 percent of the American diet is ultraprocessed, Stanford Medicine says, with ultraprocessed foods often cheaper to buy than healthier options.
Ultraprocessed foods are made with sodium, added sugars and refined grains, as well as industrial ingredients that enhance taste and texture.
However, not all ultraprocessed foods are considered junk foods. For example, yogurt and hummus are better options.
Still, June research from Tufts University has revealed that people who ate more ultraprocessed foods had worse health outcomes — even after accounting for the overall nutritional quality of the foods.
What to Watch
AI outlook — possibilities, not facts
Public health campaigns will increase efforts to reduce ultraprocessed food consumption
Likely · Within months
Open Questions
- What specific mechanisms explain the 'cocktail effect' of combined food additives on health?
- How do socioeconomic factors influence ultraprocessed food consumption across different populations?
- Are there safe thresholds for ultraprocessed food consumption that do not significantly increase health risks?




