
It is ineffective if the total calories do not exceed the standard. Eating time is the key
Liu Haowen, president of Wilme Clinic, quoted a study published in "Clinical Gastroenterology and Hepatology" in 2026 and pointed out that people who are accustomed to eating late-night snacks after dinner or before going to bed have a 36% increase in the risk of metabolic fatty liver and a 28% increase in liver cirrhosis, and even as high as 49% after excluding night shift interference; there is no significant association with skipping breakfast.
AI-generated summary
The article cites a study published in "Clinical Gastroenterology and Hepatology" in 2026. A team from Massachusetts General Hospital in the United States combined three major generations of research to track 199,155 adults who did not have liver disease for 16 years to explore the impact of eating time on the liver.
Many people think that as long as "the total daily calories do not exceed the standard" and they don't drink alcohol, eating a healthy late-night snack before going to bed will not do anything. Dr. Liu Haowen, the director of Wilme Clinic, quoted the latest research published in the gastroenterology and hepatobiliary journal "Clinical Gastroenterology and Hepatology" in 2026 in Threads "Dr. Liu Haowen" and gave all night owls a warning: What really pushes the liver to inflammation and sclerosis is often not how much you eat, but "at what time" you eat!
Liu Haowen said that he had been asked by patients, "I don't drink alcohol and only eat two meals a day, how can I have fatty liver?" Liu Haowen cited research and pointed out that a research team from Massachusetts General Hospital in the United States combined three well-known generation studies and tracked up to 199,155 adults who did not have liver disease for 16 years, with the purpose of finding out the impact of "eating time" on the liver.
When scientists corrected for age, BMI (fat or thin), "total calories" consumed daily, amount of exercise, alcohol intake, and even "eating healthy or unhealthy (dietary index AHEI)", they discovered three surprising findings:
Late-night snacking is an independent culprit of liver damage: People who are accustomed to eating after dinner or before going to bed (Late-night eating) have a direct increase in the risk of "metabolic fatty liver disease (MASLD)" by 36%!
Even the risk of liver cirrhosis is greatly increased: the same group of people who like to eat late-night snacks have a significantly increased risk of developing "liver cirrhosis" in the future by 28%; if the interference of night shift work is further excluded, the risk of late-night snacking leading to liver cirrhosis is even as high as 49%!
"Skipping breakfast" is wrongly accused: many people choose to skip breakfast when implementing 168 fasts. Research has found that after adjusting for overall living habits, "skipping breakfast" has no significant relationship with fatty liver or cirrhosis. The real fatal injury is that eating time is pushed into the night!
Why does eating at night lead to fatty liver even though the total calories are the same? Research shows that our liver has a sophisticated "circadian clock"; at night, when the body prepares to rest, the liver's "nighttime insulin resistance" will naturally increase and the energy consumption rate will also decrease.
When food is stuffed in, the liver cannot process the sugar and energy, and directly activates the "De-novo lipogenesis" channel. To put it simply: take what you eat at night and directly package it into oil droplets in your liver and store it!
If you are performing a 168 fast, or want to reverse the red letter of fatty liver on the health examination report; what you should do is not to go hungry during the day and leave it until midnight to eat; instead, try to move the dinner time forward to give the liver a clean night without having to work overtime.
☆Excessive drinking is harmful to health. Drunk driving is prohibited☆
AI outlook — possibilities, not facts
More people will adjust their dinner time to avoid eating before bed
Likely · Within weeks

Physician Wang Si-heng cited a National Taiwan University Public Health study and pointed out that the average sugar content of 700ml half-sugar hand shake drinks on the market is 46.5 grams, which is close to the daily upper limit; and 55.6% of drinks labeled as no added sugar still contain sugar. The main reason is that milk, juice and ingredients contain sugar.

Tainan Municipal Hospital held the "Youth on the Bar! Silver Hexagonal Barbell Fun Competition", attracting 42 seniors to participate. 96-year-old Shi Jinzhi successfully lifted a 45-kilogram barbell, and 91-year-old Su Yangniang lifted 40 kilograms, demonstrating the results of advanced age muscles and healthy aging.

A research team from McGill University in Canada found through experiments on mice that the interaction between a specific high-fat diet and intestinal bacteria can improve the response to immunotherapy, providing new clues to the "obesity paradox." However, it is currently limited to animal experiments and has not yet been directly applied to humans.

A survey by the Society for Community Organisation reveals that over 50% of underprivileged children in Hong Kong spend more than two hours daily on electronic devices, sparking health and addiction concerns.

Radiation oncologist Liao Zhiying pointed out that chronic inflammation promotes cancer through four mechanisms: repeated damage to DNA, continuous activation of growth signals, difficulty in cell death, and imbalance of the immune environment, increasing the risk of liver cancer, gastric cancer, colorectal cancer, etc. Reducing controllable sources of chronic inflammation is an important strategy to reduce the risk of cancer growth.

The 31st Annual Meeting of the Asian Pharmaceutical Association was held in Bangkok, Thailand. Taiwanese pharmacist Zhang Yuli was elected as FAPA president from 2027 to 2030 and will take office in January next year; former president Wang Wenfu was awarded a certificate of appreciation for 28 years of service. Lin Yijun, Chairman of the Taiwan Pharmacists Association, led a delegation to participate in "Taiwan Night" to communicate with pharmaceutical industry leaders from 16 countries and strengthen international cooperation.