
代謝科醫師楊幼琳指出,一名23歲男子因血糖控制不佳,導致三酸甘油脂飆升至6214mg/dL,背部出現發疹性黃色瘤,經低脂飲食、嚴控血糖及調整胰島素治療後一個月改善,並警告高三酸甘油脂血症可能引發胰臟炎及心血管風險。
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高三酸甘油脂血症是一種代謝疾病,當血液中三酸甘油脂水平異常升高時,可能導致皮膚出現黃色瘤,並增加胰臟炎及心血管疾病風險。
2026/09/23 13:22
代謝科醫師楊幼琳指出,23歲男子因血糖控制不佳,三酸甘油脂飆破6000,背部長滿「黃色瘤」。(圖由醫師楊幼琳授權提供)
〔健康頻道/綜合報導〕血糖飆高不只帶來糖尿病風險,也可能衍生更多健康威脅。代謝科醫師楊幼琳分享1名23歲男性糖友,由於血糖控制不佳,導致滿背長出黃色瘤(或稱黃脂瘤),經抽血檢查發現,三酸甘油脂(TG)數值竟飆破6000mg/dL、達6214mg/dL。所幸經低脂飲食、嚴控血糖,並增加胰島素劑量調整與治療,1個月後回診,背部皮膚上的黃色瘤才變小改善。
楊幼琳於臉書粉專「楊幼琳醫師」發文表示,發疹性黃色瘤(Eruptive Xanthoma)的成因,通常是TG超過2000mg/dL,以致在皮膚上形成小型堅硬且呈蠟狀的突起。一般大小約1-4毫米、表面有光澤,顏色可能呈現黃色、粉色或紅色,周圍常伴有紅暈。通常出現在背部、臀部、肩膀、手臂和大腿;雖不會疼痛,但有時會搔癢或觸痛。
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楊幼琳進一步說明,胰島素絕對或相對缺乏者,如控制極差的第二型糖尿病患者,除了可能導致高血糖、高血糖症狀、甚至高血糖危象,脂蛋白脂肪酶(#LPL)活性降低,也可能引發全身脂肪代謝失常,導致極端TG升高,有時甚至可飆升至2000–5000mg/dL以上、極低密度膽固醇(VLDL)上升、高密度膽固醇(HDL)降低,增加血管硬化及心臟病風險。
楊幼琳表示,高三酸甘油脂血症與脂肪肝相關,異位脂肪導致慢性發炎,進而增加胰島素阻抗,容易誘發胰臟炎,嚴重甚至可能引發胰臟壞死、敗血症、休克。
想要避免發生黃色瘤,楊幼琳提醒,日常應掌握低三酸甘油脂飲食原則,包括:戒菸、少酒,避免含糖、代糖,減少果糖、精緻澱粉類與加工食品,多吃魚和膳食纖維。此外,也應多運動,飲食控制總熱量,維持理想體重。

The Keelung City Health Bureau and the Pharmacists Association have cooperated to promote community-friendly pharmacies. Currently, 101 pharmacies have joined in, providing 11 services including blood pressure measurement, dementia-friendly, medication consultation, and home delivery of medications. Pharmacies can provide an average of 1 to 8 services depending on the service volume. A unified identification sign is hung at the door to improve the safety and convenience of medication for the elderly.

The World Health Organization's World Patient Safety Day in 2026 focuses on safe care for non-communicable diseases. Research shows that 1 in 6 patients receiving such care will experience preventable medical injuries, which is three times the rate in general medical conditions. Wu Honglai, chairman of the Taiwan Patient Alliance, pointed out that patients and caregivers should become important partners in safe care. Minister of Health and Welfare Shi Chongliang emphasized that patient participation is crucial to disease safety work, and unilateral promotion has limited results.

Guo Zhidong, an attending physician at the Cardiovascular Center of Cathay General Hospital, pointed out that patients with heart failure have a higher proportion of new cancers. Symptoms such as unexplained weight loss, anemia, night sweats or increased fatigue should inform the doctor to evaluate whether examination is needed. He emphasized that the two diseases share risk factors but a direct causal relationship has not yet been proven.

Xu Jiayu, director of the Nutrition Department of Taipei Rong Zhong Hsinchu Branch, reminded that Mid-Autumn moon cakes are high in calories and have too much oil and sugar. The team developed yam and date mud cakes to replace the traditional cake crust, which is suitable for the elderly and patients with chronic diseases. It is recommended to pair them with sugar-free tea and increase vegetable intake.

Grapefruit, pomelo and grapefruit contain furanocoumarins, which inhibit the CYP3A4 enzyme involved in drug metabolism in the intestines and liver, affecting the metabolism of some sleeping and anti-anxiety drugs and increasing drug concentrations. The effects may last for dozens of hours or even two or three days. Safety cannot be guaranteed by staggering the taking time alone. It is recommended to consult a physician or pharmacist before taking the drug.

Taiwan's blood donation rate ranks first in the world at 8.08%. However, the declining birthrate and aging population have led to a decrease in young blood donors and an increase in demand for medical blood. It is expected that there will be an intersection between supply and demand from 2027 to 2030. Experts call for blood donation through children's education, precise blood transfusion management, and advance blood preparation to deal with potential ischemic crises.