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Back鼻咽無癌細胞卻轉移淋巴結 彰化80歲老翁確診第四期鼻咽癌
鼻咽無癌細胞卻轉移淋巴結 彰化80歲老翁確診第四期鼻咽癌
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自由时报2 hours agoHealth2 min readChinaView translation

鼻咽無癌細胞卻轉移淋巴結 彰化80歲老翁確診第四期鼻咽癌

Quick Look

彰化縣80歲陳姓老翁因脖子左側出現多顆無痛腫塊延誤就醫,檢查後發現鼻咽無癌細胞但EBV DNA極高,癌細胞已轉移至淋巴結,確診為第四期鼻咽癌,經化療與放射線治療後病情受控。

AI-generated summary

Why It Matters

鼻咽癌與EB病毒感染、吸菸及基因遺傳有關,早期常無明顯症狀,易被忽視。

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2026/09/25 09:51

陳姓老翁的鼻咽沒有癌細胞 ,結果癌細胞都長到淋巴結。(彰化醫院提供)

〔記者顏宏駿/彰化報導〕彰化縣現年80歲的陳姓病人脖子左側長出腫瘤,摸起來像整串葡萄,因不痛不癢也就沒積極就醫,他的鼻咽並無癌細胞,結果全部轉移到淋巴結。直到雙腿水腫無法站立,才上醫院檢查,確診為鼻咽癌,且已鼻咽癌四期,經過化療和放射線治療已控制病情。

陳姓病人菸齡50年,年輕時嚼檳榔,約1年前先摸到脖子右側有1小腫瘤,幾個月後卻變到脖子左側,愈來愈愈多顆,超過10顆像葡萄一樣的腫瘤長到左脖,不癢不痛,他不以為意,直到雙腿水腫、身體虛弱才看醫生,轉介到衛福部彰化醫院治療。

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彰化醫院副院長、耳鼻喉科醫師許嘉方表示,內視鏡檢查和鼻咽病理切片,顯示陳姓病人的鼻咽沒癌細胞,抽血檢驗血液中EBV DNA高達1430 copies/ml(正常0),醫界已證實EBV DNA是鼻咽癌高敏感度和高特異性的生物標誌物。

許嘉方指出,正子攝影顯示病人的淋巴結腫瘤出現在後咽部,是鼻咽癌最易轉移部位,再加上頸部淋巴結病理切片表現出鼻咽癌細胞的特性,癌細胞全部轉移至淋巴結,確這是第四期鼻咽癌病例,通過鼻咽癌重大傷病申請審查。

許嘉方說,鼻咽癌是常見在鼻腔後方喉嚨交界處的惡性腫瘤,好發於中壯年,主要成因與基因遺傳、EB病毒(EBV)感染及抽菸等環境因素有關,陳姓病人若早一點就醫檢查,應該能在鼻咽部發現癌細胞,後來可能全部轉移而沒被發現,也可能原發部位癌細胞被免疫系統抑制導致完全消退,使得病情判斷不易。

鼻咽部癌細胞非常容易擴散到頸部的淋巴結,許多患者往往摸到脖子出現一個或多個不會痛且無法移動的腫塊才就醫發現,許嘉方建議,如果脖子出現腫塊,不痛腫塊比會痛的腫塊更危險,一定要儘快就醫,以釐清是良性或惡性。

正子攝影顯現左脖淋巴結腫瘤一大串。(彰化醫院提供)

Open Questions

  • 陳姓病人是否有家族癌病史
  • 其EBV DNA高達1430 copies/ml的具體成因為何
  • 治療後是否需要長期追蹤EBV指標

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