
中國中南大學湘雅醫院研究團隊分析英國生物資料庫超過45.8萬名成年人資料,發現肌少症前期及肌少症者感染風險增加,尤其與呼吸道感染及敗血症關聯明顯;研究指出規律肌力訓練有助維持肌肉健康,但無法證明肌肉流失直接造成感染增加。
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肌肉隨年齡逐漸流失,不只是力氣變小、走路或爬樓梯比較吃力,最新研究發現,肌肉量不足還可能與感染風險增加有關,尤其是呼吸道感染及敗血症。
2026/09/06 11:27
研究發現,肌肉量不足者感染及敗血症風險較高;規律肌力訓練有助維持肌肉健康。示意圖,圖中人物與新聞無關。(圖取自shutterstock)
〔編譯陳成良/綜合報導〕肌肉隨年齡逐漸流失,不只是力氣變小、走路或爬樓梯比較吃力,最新研究發現,肌肉量不足還可能與感染風險增加有關,尤其是呼吸道感染及敗血症。研究團隊分析超過45.8萬名成年人資料,發現肌肉健康與人體抵抗感染的能力可能存在關聯。
據《華盛頓郵報》報導,中國中南大學湘雅醫院研究團隊分析英國生物資料庫(UK Biobank)逾45.8萬名40至69歲成人資料,依肌肉量、肌力及身體活動表現,將受試者分為沒有肌少症、肌少症前期及肌少症。結果顯示,後兩組的感染風險都較高,其中與呼吸道感染及敗血症的關聯最明顯。
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肌少症是肌肉量與肌力逐漸下降的狀態,通常約從30歲開始,每10年可能流失3%至5%的肌肉,到了60歲左右才較容易明顯感受到。肌肉除了支撐日常活動,也與人體承受疾病、手術及其他身體壓力的能力有關。
研究發現,肌少症前期及肌少症患者,不只泌尿道與皮膚感染風險較高,呼吸道感染及敗血症的關聯尤其明顯。研究團隊認為,肌肉流失可能與慢性發炎、營養不足及免疫反應受損等因素同時存在,部分發炎指標也可能解釋其中一部分關聯。
不過,這項研究屬於觀察性分析,不能證明肌肉流失直接造成感染增加。研究人員也無法排除感染導致肌肉量下降,或其他健康因素同時影響肌肉與感染風險的可能性。
年輕人肌肉過早流失 風險反而更高
研究中的年輕族群分析也出現一項現象,較年輕但已經出現肌少症的人,感染風險甚至高於年長的肌少症患者。研究團隊認為,年輕人若過早出現明顯肌肉流失,可能反映其他潛在健康問題。
報導引述梅約醫院(Mayo Clinic)老化研究專家指出,肌肉量較充足的人通常比較能承受手術或化療等身體壓力,這也讓肌肉健康可能與人體面對感染時的恢復能力產生關聯。
目前預防肌肉持續流失,仍以規律運動及肌力訓練為主。美國疾病管制暨預防中心(CDC)建議,健康成年人每週至少進行2次全身肌力訓練。研究也顯示,即使75歲以上才開始重量訓練,仍可能增加肌肉並改善日常活動能力。至於增加肌肉是否能進一步降低感染機率,目前仍沒有足夠證據證實;但維持肌力、適當運動,仍是健康老化的重要一環。
AI outlook — possibilities, not facts
未來研究將探討肌力訓練是否能直接降低感染機率
Possible · Within months

Director of Hong Yongxiang Clinic pointed out that Mr. Chen, a patient with chronic renal failure, drank coffee with sugar and creamer every day, which led to high blood phosphorus and declining kidney function. However, he emphasized that coffee itself does not damage the kidneys, and the key is how he drinks it. It is recommended to choose sugar-free black coffee, avoid creamer and refined sugar, and mix it with an appropriate amount of extra cold-pressed virgin olive oil at high speed to reduce health burden and protect the kidneys.

If you have unexplained severe fatigue, memory loss, and muscle aches that last for more than six months, and there are no abnormalities in hospital examinations, you may be suffering from chronic fatigue syndrome. Chen Min, an expert from the Jiangsu Provincial Hospital of Traditional Chinese Medicine, suggested systematic conditioning of the five internal organs, qi and blood, through TCM syndrome differentiation and lifestyle adjustment.

The article points out that controlling blood lipids requires not only reducing fat intake, but also paying attention to the endogenous fat converted from polished rice and white flour. The elderly should choose oils rich in monounsaturated fatty acids and omega-3 polyunsaturated fatty acids, such as olive oil, tea seed oil, etc., eat egg yolks in moderation to obtain the benefits of lecithin, and replace some refined white rice noodles with whole grains such as oats and buckwheat to increase soluble dietary fiber to absorb cholesterol and promote excretion.

The Kaohsiung Hunei Digital Opportunity Center partnered with the Gongguan Community to launch a cloud-based health assessment tool, helping seniors measure and archive their blood pressure and heart rate daily in the cloud for easy medical reference and family sharing, improving healthcare quality for the elderly, with plans to expand to more communities.

Public health physician Cai Bingjian cited an interim analysis in the magazine "Food & Function" and pointed out that in the trial of Mediterranean diet plus probiotics, the metabolite changes of Spanish elderly participants showed an increase in the flexibility of energy switching, and some metabolites were related to cognitive scores. However, the study was only a correlation analysis and could not claim to prevent dementia.

A food poisoning incident broke out at Café de Coral, a Hong Kong-style restaurant in Tianhe City Mall in Panyu, Guangzhou, on the evening of August 28. As of September 4, a total of 14 people felt unwell, and 12 of them were sent to the hospital. A 13-year-old boy developed severe abdominal pain, vomiting, and diarrhea after eating Gillette pork chop and egg fried rice with Italian meat sauce. He developed severe dehydration, confusion, and shock. He was urgently transferred to the Pediatric Intensive Care Unit of Panyu Central Hospital, and the hospital issued a critical illness notice. The Guangzhou Panyu District Market Supervision Bureau has intervened in the investigation and requires comprehensive disinfection and sterilization and improvement of food processing procedures. The inspection results have not yet been released. The person in charge of the Café de Coral brand stated that the store has been closed for rectification. It is initially suspected that the eggs are contaminated, and the store will adjust the food supply method and strictly manage the catering production and environmental sanitation of all its stores.